Telmisartan is an anti-hypertensive drug that exhibits poor aqueous solubility. In this work, salt formation was utilized to address this issue. Three hydrochloride salts of telmisartan (TELHCl), a trihemihydrate hydrochloride salt (TELHCl-Hyd), and …
Salt cocrystallisation method successfully suppressed hydration and lowered the dissolution rate of the pharmaceutical salt crystals.
In this study, we attempt to simultaneously improve the photostability and solubility of epalrestat (a drug used for neuropathy treatment) by preparing epalrestat–betaine zwitterionic cocrystals and characterize the physicochemical property …
Epalrestat, a drug for diabetic neuropathy, was able to form a cocrystal with a pharmaceutically acceptable coformer of caffeine.